Ukuhlolwa kwezidakamizwa zesimila ukuze kwenziwe ucwaningo

Ukuhlolwa kwezidakamizwa ze-tumor, okubuye kwaziwe ngokuthi ukuhlolwa kwezidakamizwa ezilwa nomdlavuza noma ukuhlolwa kwezidakamizwa zomdlavuza, kubhekisela ohlelweni lokuhlola imithi ehlukahlukene ukuze kutholakale leyo engakwazi ukwelapha izimila ngempumelelo.Lokhu kuhlolwa kwenzelwa ukwembula izindlela zokwelapha ezingase zibe khona ezigulini ezinomdlavuza.Idlala indima ebalulekile ekwakhiweni kwemithi emisha kanye nokuthuthukiswa kwezindlela zokwelapha ezikhona.

Umgomo oyinhloko wokuhlolwa kwezidakamizwa zesimila ukukhomba izinhlanganisela ezingavimbela ukukhula noma ukubulala amangqamuzana omdlavuza kuyilapho konga amaseli anempilo.Le ndlela, eyaziwa ngokuthi ukwelapha okuqondisiwe, ihlose ukukhulisa ukusebenza ngempumelelo kokwelashwa kuyilapho kunciphisa imiphumela engemihle.Ukuhlola kuhilela ukufaka ngaphansi kwamangqamuzana omdlavuza, ngokuvamile atholakala kumasampula esimila kuye ezinhlobonhlobo zemithi ukuze kutholwe ukusebenza kwawo okungaba khona ekubulaleni amangqamuzana omdlavuza.

Kusetshenziswa amasu ahlukahlukene ekuhlolweni kwezidakamizwa zesimila, njengokuhlolwa kwe-high-throughput, okuvumela ukuhlolwa okusheshayo kwezinkulungwane zezinhlanganisela.Le ndlela yenza abacwaningi bakwazi ukuhlonza abantu abathembisayo abangase baphinde bahlolwe ngokusebenza kwabo, ukuphepha, kanye nezicelo zomtholampilo ezingaba khona.

I-MingCeler inikeza uhla olugcwele lwezinsizakalo zokuthuthukiswa komtholampilo ezisezingeni eliphezulu zokuhlolwa kwezidakamizwa ze-oncology kanye nokuqinisekiswa, okuhlanganisa ukuhlonza okuhlosiwe nokuqinisekiswa, ukuhlolwa kwamaselula e-vitro, ukwakhiwa kwemodeli yesimila se-vivo, i-vivo pharmacology, i-pharmacokinetics, i-pharmacodynamic kanye nokuhlola ubuthi obuyisisekelo.

Ngokuya ngezidingo zamakhasimende ethu, singahlinzeka ngezifundo ezijulile zokusebenzisa imishini.